HTTP/1.1 200 OK Cache-Control: no-cache, private Content-Type: text/html; charset=UTF-8 Date: Sat, 28 Nov 2020 04:41:42 GMT 日本三级韩国三级
Jump to main content
Jump to site search

Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

但他并没有做到这些。所以普莱斯蒂聪明的在他还有交易价值的时候把他送走了。
Age: 56

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 大胆预测,涂料市场将会这样变化
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

GAINS AND LOSSES IN A CHANGING WORLD
全球重量级的央行家和政府官员周六表示,对一些新兴经济体脆弱性的担忧以及近期金融市场的剧烈波动,应该不会挫伤人们对今年全球经济形势的“谨慎乐观”态度。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

失业率的大幅下降的实际效果将会有所体现

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

美国的排放量在经过了最近几年的持续下降后,提高了2.9%。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Effective email marketing involves more than occasionally blasting out a newsletter. To build an effective email marketing strategy, you need a tool packed with functionality. MailChimp seems to be the best system out there, offering elegant, intuitive newsletter templates, advanced list segmentation features and marketing automation capabilities.
TAXES: Approximately $41,684 a year
A new MIT white paper, ominously entitled "Are You Prepared for the Supply Chain Talent Crisis?," bears that out. Supply chain managers need sophisticated tech skills, sure, but they also have to be adept at "high-order diplomacy," expert at general business strategy and problem solving, and able to "thrive in ambiguity," the study says.
It seems that Christmas time is here once again, and it is time again to bring in the New Year. We wish the merriest of Christmas to you and your loved ones, and we wish you happiness and prosperity in the year ahead.又该迎接新的一年了。我们向你及你的亲人们致以最美好的祝福,愿你在新的一年里事业兴旺,幸福美满!

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

优秀的老板知道公司或客户需求和他/她的员工需求之间一定存有一个平衡度。优秀的老板都喜欢倾听员工的心声和同他们交流可能存在的一些问题,因为他们知道员工快乐工作效率才会更高。
伦敦商学院重回榜首,一定程度上归因于毕业生薪资水平最高,达到16.7万美元,同时性价比排名第二。该学院在国际课程体验方面排名第一,在校友流动性方面排名第二。
"There's a new type of wealth creation coming out," he told Reuters, adding China was having to adapt as the wider economy was "very materially slowing down".
May your New Year be filled with special moment, warmth, peace and happiness, the joy of covered ones near, and wishing you all the joys of Christmas and a year of happiness.

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 18种情形失信企业将被列入黑名单
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

['k?pirait]

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

单词conduct 联想记忆:

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

The pair came out with a spree of punch lines, dishing them around the Beverly Hills Hilton, much to the delight of its starry audience. Mr. Damon, Meryl Streep and, naturally, Mr. Clooney were among the targets. Ms. Fey particularly had the crowd roaring with a description of 'Gravity,' which stars Sandra Bullock and Mr. Clooney.
A tender love story between a teenager and an academic, set in Italy.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

愿你的新年充满温馨,祥和,与亲人团聚的快乐,祝乐陶陶,新年乐无限。
根据美国海洋和大气管理局的数据,美国本土今年1月至11月的气温是有史以来每年前11个月的最高记录。2012年还将超过1998年,成为美国有记录以来最热的一年。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

在观影从始至终,我都在问自己一个问题:这部电影到底在讲什么……这部电影的主题仿佛一锅杂烩,并不明晰。我希望制片人也在问同样的问题。
《受虐待经历影响的瑞典“女权主义外交政策”倡导者》(Sweden’s Proponent of ‘Feminist Foreign Policy,’ Shaped by Abuse)

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

The Warriors are one of the best teams in NBA history, and you can put their championship run up against any team in NBA history for the best playoff performance ever. But there's also a legitimate question of what this means for the sport. If the best or second-best player of all time stands no chance against this team, what does it mean for the sport's competitiveness? It hasn't been a problem so far, thanks to an extremely wild offseason, but the question remains: what happens to a competitive sports league when it's not truly competitive at the highest level?
除了众多受过教育的劳动力可供选择,企业也被亚利桑那州的亲商监管环境所吸引,在莫卡特斯中心(Mercatus Center)发布的美国50个州商业自由度排行榜上,亚利桑那州排名第13位。这项研究援引亚利桑那州的劳动权利法、责任法和土地征用权改革作为有利条件。
Most technology developers are seeing app use grow and web use decline. That means companies have to have strong, fast, meaningful mobile platforms and those that don't lose customers.
2016年,高管薪酬均值达709万元,同比增长8%,跑赢了我国国内生产总值6.7%和人均可支配收入6.3%的增速。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 建材市场售后服务的“疑难杂症”
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

['spekju.l?tiv]

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

4.阿迪达斯。品牌喜爱度:35%/排名:25
译文属可可原创,仅供学习交流使用,未经许可请勿转载

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

而其他的队伍还有在尝试赢球的。小牛队,在3-13的战绩面前,骄傲地说他们不会垫底。但是,明年被认为是近年来最好的NBA选秀,有Markelle Fultz, Jayson Tatum, Lonzo Ball, Josh Jackson, Harry Gile, OG Anumoby, Ivan Rabb……等等优质球员。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

[m?:'t?liti]

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

2. Will China's stock market climb back to 6,000 points?
Upgrades to the country's industrial structure in which labor-intensive industries are being moved out of metropolitan areas contributed greatly to the demographic change, Peng Xizhe, dean of the School of Social Development and Public Policy at Shanghai-based Fudan University, told the Global Times on Tuesday.
In those days, of course, Rembrandt was the gold standard. But the Dutchman and his fellow old masters have fallen out of fashion and are no longer as coveted by collectors and investors.
单词toxic 联想记忆:

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

《生活大爆炸》中绝不缺少天才。不只是因为这部剧向观众展示了很多绝顶聪明的科学家,同时,演员玛伊姆·比亚利克还拥有神经学博士学位。因此,演员们想要在剧中展示他们的聪明才智,并将整部剧做到精益求精,这也不足为奇。剧中谢尔顿和莱纳德的公寓里有一块很大的白板,这对铁哥们几乎在处理任何事时都会用到它,从完成从学校带回来的工作,到决定是否等到看完最新一部《蜘蛛侠》再吃饭,都离不开这块白板。
In my country, we make so much waste, we buy and throw away, buy and throw away, and yet northern countries will not share with the needy. Even when we have more than enough, we are afraid to lose some of our wealth, afraid to share. 在我的祖国,我们制造了如此之多的垃圾,我们购买商品,我们随之丢弃,买来,再丢弃。然而有些国家,有些人,却不会分享给那些真正需要的人们,甚至他们拥有的远远超过自身需要的时候。他们害怕分享,害怕失去自己的财富。
不过在这一通胡闹之余(主持人蒂娜?费举杯道:致这个美好的混乱之夜),本届金球奖(Golden Globes)颁奖典礼还是清醒地把多项重要大奖颁给了各个夺奖热门。戴维?罗素(David O. Russell)电影作品《美国骗局》(American Hustle) 揽入包括最佳喜剧片在内的三项金球奖,成为当晚最大赢家。历史剧情片《为奴十二年》(12 Years a Slave)虽在另外六个竞赛单元中失利,但最终斩获了最佳剧情片奖。
The approach has in some cases moved from the political fringes into the mainstream. Some leaders from Britain’s center-right, governing Conservative Party, for example, helped push a British exit, and since the referendum the new Conservative prime minister, Theresa May, has signaled sympathy with white identity politics.
《极盗车神》日前入围了美国电影评议评选的十佳电影榜单,烂番茄评分93%,票房收入超过1亿美元。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

曼谷王者归来!
Think you’ve had some bad job interviews this year? This survey is guaranteed tcheer you up (unless you happen tbe part of it). When staffing firm OfficeTeam asked 600 managers across North America tdescribe the most embarrassing interview blunders they had seen in 2014, here’s what they said.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

9.Yeah, I was a badass on my high school football team! – Because I want to be seen by others in an even stronger light than I see myself。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

['hedwei]

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

然而,007系列电影主题曲却并没有人们想象的那么历史悠久。第一部《诺博士》和第二部《俄罗斯之恋》没有开场曲,而是安排了管弦乐。《诺博士》甚至插入了《三只瞎老鼠》的怪异演奏。随后,《女王密使》才开始有了开场曲,并且在影片的中间和结尾插入了主题曲。
?大雪已经降落在西弗吉尼亚州,在韦伯斯特斯普林斯雪的厚度达到17英寸。国家气象局警告说更多的雪还在路上。
Inside larger technology companies, female employees will be hoping for signs of change in pay and promotions — but will also be on guard, as a men’s rights backlash brews in some corners of Silicon Valley.
● “奥巴马签署行政令禁止学校读效忠宣言”

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

针对那些对比较世界各地的学校有兴趣的学生,《美国新闻与世界报道》近日发布了第四版全球最佳大学年度排行榜。
The S&P 500’s total return of 14% this year was 40% higher than its 25-year average annual gain. Wall Street’s chief strategists spent much of the last 12 months revising their targets higher from behind. The index printed over 50 all-time record closes, with nearly all investment management professionals racing to at least pull even. A few characteristics made the U.S. stock market particularly difficult to keep up with this year.
无论是电视剧,还是正在拍摄的电影版本,都是改编自台湾大宇公司旗下著名的角色扮演游戏(RPG)《仙剑奇侠传》系列。这款电子游戏也被许多玩家视为中国最棒的角色扮演游戏。
办事处副局长卢华东说:“自治区已投资40亿元人民币(约合6亿美元),用于推动贫困地区特色的产业,去年重新安置了77000名贫困人口。”

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Rankings for Greece, Italy, Portugal and Spain fell dramatically because of the impact of the eurozone crisis, while Egypt, Myanmar and Saudi Arabia registered large falls in the wake of recent political and civil turmoil.
[nju:'trin]

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: 盘点:2017卫浴行业八大“瓶颈”
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

If you want a refrigerator with a screen, might as well just stick an iPad on it. Samsung unveiled a smart refrigerator this summer that connects to wi-fi to help manage groceries and leave notes behind for family members.
Despite the seemingly extensive target vetting on May 7 the Chinese embassy in Belgrade was struck by five Joint Directed Attack Munition satellite-guided bombs delivered by U.S. Air Force B-2 Spirit bombers. Three Chinese journalists—Shao Yunhuan of Xinhua and Xu Xinghu and his wife Zhu Ying of the Guangming Daily—were killed in the attack. Twenty other Chinese nationals were injured five seriously.
We will accelerate the development of emerging industries.
问:对于你的作品在西方广受欢迎一事,你是怎么看的?
美国的排放量在经过了最近几年的持续下降后,提高了2.9%。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

"There's a new type of wealth creation coming out," he told Reuters, adding China was having to adapt as the wider economy was "very materially slowing down".
时间:2009-10-22 编辑:vicki
北京2016年受理外籍人士及其家属永久居留申请较2015年增长426%。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

However, this may be balanced by a decline in European and Chinese investment, with the impact of the latter on global trade heightened if China was to engineer a partial switch from investment in resource-heavy construction to forms of infrastructure spending such as water purification that are not very commodity intensive.
为保证更快的经济增长就必须要要消除美联储所担忧的另一个恶魔:通货紧缩,或者说价格下降。Baumohl 称“经济增长达到3%以上,并且自90年代以来新增了大量工作的国家发生通货紧缩几乎是不可能的”。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 钢铁业低迷:亏损企业常年不倒
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Sixty-one percent of Chinese college students who graduated in 2014 are satisfied with their current jobs, a survey has revealed.
"电梯外面很多人,有我的老师,别的家长们,他们看起来都非常焦急,"孙轶潇在获救后表示。
adj. 透视的

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

其关于朋友间爱情、事业、友谊的主题仍然与今天的年轻人息息相关。
从一个孩子的视角,讲述佛罗里达州一家汽车旅馆社区的生活。
It was the season of Light, it was the season of Darkness…

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 华东水泥价格再次上扬
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

France, along with Belgium, has seen the largest numbers of volunteers leaving to join the Islamic State jihadist group, which has seized large parts of Syriaand Iraq.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

But John Davies, head of institutional investment in the Hong Kong team at CBRE, the property services business, says that lower prices should make the market more reliable. “The market is showing characteristics of a mature market, which institutional investors understand better,” he says.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

英语中,男女用语的7个大不同
发型。略长的卷发——蛤?你不是自来卷哦?小可怜,那你只好每晚带着卷发夹入睡了。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Once you grow your hair slightly longish, be sure to play with it at every opportunity.
10. China watchers inthe United States will continue to postulate China’s declining growth rate inthe face of evidence that it is stable at over 7%. China will grow fasterin 2014 than in 2013.
Five development concept of innovation, harmonization, green, openness and sharing
他说,杂志和作者在这起最近发生的丑闻中都有不可推卸的责任,声明中还说,《肿瘤生物学》在2015年就已经因同行评议过程存在类似问题而撤销一些论文。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

此外,菲亚特一款引擎不仅首次进入《沃兹汽车》十大引擎榜单,而且还是一款电动发动机,这就是起亚500E所使用的83千瓦发动机。遗憾的是,该车只在加利福尼亚州发售,但是如果汽油价格上涨至每加仑4.00美元大关或以上,市场力量可能说服这家汽车生产商进行更大范围的分销。
adj. 泰然自若的,镇定的;摆好姿势不动的,静止的;平

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

但对于北京来说,若能在特朗普让美国退出TPP后不到一年的时间里达成RCEP协议,将是一场巨大的胜利。
So, before the world gets the better of you and slaps a title on your forehead, create a unique manifesto of what you think you are.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

PPI已连续下降44个月,反映出建房材料和原料的供应过剩,以及重工业的产能过剩。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

它促使特朗普当选不仅与选举中的投票数不符,而且也没有反映出亚历山大.汉密尔顿(Alexander Hamilton)想要的那种对候选人德行的判断。
新年的祝福,平日的希冀,愿你心境祥和、充满爱意,愿你的世界全是美满,
outrage
2.喷气背包

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 今后,名下有多少套房一查就知道
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

3.Oh, yeah. That makes sense. – Because option B involves admitting that I am clueless。
China's employment situation is generally stable in the first quarter of 2016, said Li Zhong, Spokesman of the Ministry, adding that the economic downturn and structural reform, however, make employment more difficult.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

会,即便真实的GDP增速未超过这个数字。关于中国真正的(相对官方数据而言)GDP增长率的猜测,已经衍生出一个由相关经济学专家组成的作坊式行业。官方数据看似稳定而美好——有人怀疑中国有关部门对数据进行了“美化”,调整了一些数字、使其符合增长目标。因此,即使2018年中国的增长磕磕绊绊,官方的增速也几乎肯定会高于预定的6.5%。
Accounting and finance grads will be in demand too, the poll says. Note to college students already looking ahead to the summer: 52% of employers in the survey said they prefer to hire graduates with internship experience.
普京对俄罗斯经济做出积极评价。他说,经济已渡过危机,至少渡过了危机的高峰。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

5. "Dexter" (3.1 million)
Two days ago here in Brazil, we were shocked when we spent some time with some children living on the streets. And this is what one child told us: "I wish I was rich and if I were, I would give all the street children food, clothes, medicine, shelter and love and affection." 在巴西,我被2天前见到的情景震惊了,那时我和当地的小孩在玩耍,其中一个小孩说:“我希望我能富裕起来,然后我会给这个街道所有的小孩饭吃,给他们衣服穿,医疗,住房和爱”。
2016年中国迅猛发展的网红经济可能会达到87亿美元

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

These artificial eyes have indeed restored sight to blind mice. And the follow-up experiments on monkeys offer a lot of hope for eventual trials on humans because monkey and human retinas work similarly.
"Protections that promote equality and diversity should not be conditional on someone's sexual orientation," he wrote. "For too long, too many people have had to hide that part of their identity in the workplace."

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

Frankly, this is unlikely to be ready in time for next year, but we'll include it just in case. The second film from Laszlo Nemes, who won the foreign language Oscar earlier this year for Son of Saul, is a coming-of-age drama set in Budapest just before the first world war.
The remains of the monarch -- depicted by William Shakespeare as a monstrous hunchback and often viewed as one of English history's greatest villains -- will now be solemnly reburied in the local cathedral.
“尼克是一位优秀的产品思想家,”雅虎移动与新兴产品高级副总裁亚当卡恩(Adam Cahan)说,“他的确代表了他在思索的事物和‘移动’真正内涵的跨世代转变。新一代不仅仅是以移动为先,而且是以移动设备为唯一上网工具。这是一种不同的视角。”

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

还有哪对系列电影的荧幕情侣可以像《暮光之城》的克里斯汀?斯图尔特和罗伯特?帕丁森这样成功开创戏路呢?两个人都成为了影坛名角。帕丁森在最新作品《好时光》中延续了他近年来这种让人几乎认不出的造型风格。在《迷失Z城》中,他把自己打扮成胡子蓬乱的眼镜男,如今他又把头发染成亚麻色,变身为一个试图在纽约完美做案,结果却让患有发育性残疾的弟弟(本?萨弗迪饰)被捕的银行抢劫犯。他试图用盗取的钱来给弟弟交保释金,结果麻烦接踵而至。很多的麻烦。除了饰演弟弟一角外,本?萨弗迪还和自己的哥哥约书亚?萨弗迪共同执导了这部电影。《好时光》入围了今年戛纳电影节的主竞赛单元,参与角逐金棕榈奖。该片于11月3日在日本上映,11月17日在英国和爱尔兰上映,11月23日在希腊上映。(资料来源:A24制片公司)
“我明天还要上学,不能晚睡。” 张天羽如是说。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

The index fell from 50.4 in October to a six-month low of 50.0.
6. 减少饱和脂肪摄入可以帮助保持记忆力
adj. 社会的,社交的

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

抓好金融体制改革。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

威廉姆斯指出,来自巴西、越南、台湾和智利的11月初数据表明,出口形势自10月以来持续改善。
“…started swearing during the interview.”

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Release date: 2015
Inclusive and green finance

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 人民时评:答好经济发展新考题
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

The new numbers, reported by a tracking initiative called the Global Carbon Project and published in the journal Nature Geoscience, came on the eve of a United Nations summit meeting meant to harness fresh political ambition in tackling climate change. Scientists said the figures showed that vastly greater efforts would be needed to get long-term global warming within tolerable limits.
时间:2010-03-09 编辑:vicki

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

你可能从未想过一根皮带可以与人工智能相结合,但Belty做到了,并使它看起来很时尚。这个belty会让你不自觉就觉得,“为什么我需要这个?”然后你想可能会是,“如果是黑客入侵,他们把它系得很紧我不能呼吸该怎么办?”第一个问题是合理的;第二个问题有些牵强,但如果它让你三思而后买这个产品,这并不是一件坏事。
In 2018, more business leaders will channel a potent combination of digitalisation, generational change and growing diversity, to streamline their hierarchies, distribute responsibility, and transform their organisations.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 政策演进 住房制度体系再优化
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

4. 欧佩克的下一步行动。说到去年的油价暴跌,石油输出国组织(OPEC)起了很大作用(或者说要承担很大责任)。虽然许多评论人士都说欧佩克保持原油产量不变无关紧要,然而,仅油价在该组织11月份会议过后出现暴跌这一事实便充分证明了该组织对油价走势的影响力。目前,欧佩克——更确切地说是沙特——仍在坚持己见,毫无下调生产配额的迹象。2015年这一情况是否会得以延续,仍有待观察。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

年龄对詹姆斯仍不是问题
Recipient: Their Royal Highnesses The Duke and Duchess of Cambridge (joint winners)
“FKA细枝”(FKA twigs),《两星期》(Two Weeks),Young Turks
Take multiple measures to cut costs.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Play up being smarter than everyone, develop some obvious insecurities. Forget social skills if you happen to have any.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

That possibility was backed up by a list of top-tier cities the statistics bureau began tracking recently
This so-called “playground for millionaires” is now open to everyone. The wallet-friendly hotels, guesthouses and self-catering apartments make tours affordable. With more than 100 divine islands scattered on the Indian ocean, many activities await, such as sunbathing, fishing, diving, sailing, and going on boat tours. The Seychelles islands are blessed with a warm tropical climate all year round, so you can go there whenever you want.
《请以你的名字呼唤我 》

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Star risers
发行于2013年的《炫富帮》是一部语带讽刺的犯罪剧情片,记录了一帮好莱坞山高中生的冒险,他们偷到了当地名人的家里。少年们进入梅根·福克斯和帕丽斯·希尔顿这样的偶像家,偷走现金、衣服、手袋和珠宝,用来模仿杂志上让他们羡慕的奢华生活。在朋友圈炫耀战利品的照片后,他们终于被抓进了监狱。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

中央纪委国际合作局局长腊翊凡表示:“在中共中央的领导下,我们将扩大与有关国家的司法合作,使腐败的外逃人员不存在“避罪天堂”。
根据一项针对技术发展的国家规划,到2020年时,研发经费的目标是要达到GDP的2.5%。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

But if the U.S. can avert that Washington-made crisis, the outlook for workers finding jobs is actually looking pretty good for next year. For one thing, the damage of superstorm Sandy will have to be repaired, meaning jobs in construction and retail. Businesses, meanwhile, which have held off investing and hiring because of uncertainty over the fiscal outlook, might finally open their wallets. That means more jobs, too.[qh]

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

The base hopes to keep up public awareness of pandas and the necessity of conservation of their natural habitats while Increasing the wild population by reintroducing individuals into areas in China where populations have declined.
Not every band can sound fresh 40 years into a career, but not every band is Blondie.
单词encourage 联想记忆:

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

国内生产总值达到74.4万亿元,增长6.7%;
摩根大通公司下滑至第4名,其总综合得分位居中国农业银行之后。去年名列前10强的两家欧企——荷兰皇家壳牌和汇丰控股,今年仅分别排名11名和14名。
《圣鹿之死》
Iron Man was Downey’s only movie of 2013, while Johnson had one huge film, Fast & Furious 6; one big film, G.I. Joe: Retaliation; and two smaller films. Together they added up to $1.3 billion at the global box office.

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 四月涂料市场动态大盘点
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

“有1400人出境去参加圣战,加入叙利亚和伊拉克境内的恐怖主义组织。” Valls告诉BFMTV。
The deal makes a millionaire of 17-year-old Mr D’Aloisio, who taught himself to write software aged 12 and will join Yahoo’s London office while he continues his studies at school.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Without a cellphone at hand, Sun tried yelling to get the attention of people outside, but no one responded as time passed by.
A cheery New Year hold lots of happiness for you!
In the original casting, Michael Keaton was set to play the character. However, ABC executives begged the writers and producers to keep Jack alive. They believed the character was too likeable to die off so quickly. The writers agreed. Michael Keaton was not interested in signing up for a long-running show. Instead, the role of Jack was given to Matthew Fox. The rest is TV history.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

Cnzz.com的报告说,目前中国3.38亿网民中有将近三分之二都是网络游戏玩家。报告说,中国网络游戏行业目前占据了互联网经济总规模的半数以上,在未来还将以每年20%的速度增长。
从一开始,社交网络就被有效地隔离在互联网之外。比如,Facebook的海量内容通常不会显示在谷歌( Google )搜索结果之中。但是否非得是这种情形?比方说,Twitter搜索结果自动出现在一个标准的谷歌搜索显示页面,岂不是更方便?再比如,当你搜索Yelp时,为什么关于某家餐厅的最新Twitter消息没有显现出来呢?由于利益相悖,不同社交网络往往把各自的内容封锁在专利保护墙之内,但也有不少工具致力于创造性地弥合这道鸿沟。需要说明的是,本文作者的公司已经开发出了这样一种工具。

Spotlight

Advertisements